Surface Chemistry (Polymer)
Polymer materials play a crucial role as substrate platforms in the fabrication of devices for many biotechnological applications. The success of these materials should be credited to their malleable surface properties as well as the adaptation of conjugation reactions to the material surface. The biointerface properties of these polymer materials—which include the ability to control the presentation of biomolecules with precisely defined chemical topology, smart response with respect to environmental stimuli, multiple functions that are simultaneously activated, and surface gradients—lead to successful device/material performance and efficacy.
Furthermore, biomolecular engineering technologies have provided the key to success in using these polymer materials. The use of physical approaches or chemical means to install biological functions onto polymer materials is of interest within this area of research. From a physical point of view, the ability to control biomolecules at the solid/liquid interface requires adequate knowledge and understanding of surface interactions, transport phenomena of interacting molecules, interactions with external stimuli, and surface functional groups. From a chemical point of view, the conjugation reactions seek a fast reaction time, mild reaction conditions, and more importantly, the specificity to achieve successful conjugation in the vast array of functionalities present in biological microenvironments.